Anesthesia and Analgesia in Laboratory Animals (American by Dennis F. Kohn, Sally K. Wixson, William J. White, G. John

By Dennis F. Kohn, Sally K. Wixson, William J. White, G. John Benson

Anesthesia and Analgesia in Laboratory Animals focuses totally at the specified anesthetic, analgesic, and postoperative care specifications linked to experimental surgical procedure. backed by means of the yank collage of Laboratory Animal medication, this informative paintings offers the reader with brokers, equipment, and methods for anesthesia and analgesia that ascertain humane and winning procedural results. Key beneficial properties* specializes in a wide selection of animal species utilized in study* presents a accomplished evaluate of the pharmacology of anesthetics and analgesics* comprises tracking of analgesia and anesthesia* Organizes issues by means of species for brokers and strategies of supplying anesthesia, analgesia, and post-op care to animals* No different American textual content is dedicated completely to this subject

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35, 605-612. Forsythe, D. , Payton, A. , Myers, P. , Clark, J. , and Snipe, J. R. (1992).

E. Detomidine 1. Description Detomidine is a selective et2-agonist that was developed in Finland for use in horses and cattle. , 1993; Salonen, 1992; see series of articles edited by Lindberg, 1986). The in vitro oL-adrenoceptor interactions of detomidine are similar to medetomidine, although there are differences in potency, both in vitro and in vivo, which are small relative to xylazine. Detomidine is a sedative and potent analgesic in rats and mice, but does not lead to loss of the fighting reflex, even at high doses (Virtanen, 1986).

Fed. , Fed. Am. Soc. Exp. Biol. 39, 1584-1591. Altura, B. , and Altura, B. M. (1975). Pentobarbital and contraction of vascular smooth muscle. Am. J. Physiol. 229, 1635-1640. American Veterinary Medical Association (AVMA) (1993). 1993 Report of the AVMA Panel on Euthanasia. J. Am. Vet. Med. Assoc. 202, 230-249. Atkinson, P. , Taylor, D. , and Chetty, N. (1985). Inhibition of platelet aggregation by ketamine hydrochloride. Thromb. Res. 40, 227-234. Aurori, K. , and Vesell, E. S. (1974). Comparative stimulatory effects of four phenothiazines on hepatic microsomal enzymes.

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